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Ready to Conceive? What to Know Before You Start Trying

Wednesday, 24 February 2016 04:14

If you want to have a baby, there are things you need to know–beyond the birds-and-bees basics–that can help enhance your fertility. We talked to our experts for advice on getting to that positive pregnancy test sooner:

Know Your Cycle

As you learned in biology class, the best time to conceive is right around ovulation. But do you know when you’re ovulating? “As soon as you start thinking about trying to get pregnant, it’s important to become more aware of your cycle,” says Bernadette Donovan, a One Medical Group nurse practitioner in San Francisco specializing in women’s health. Ovulation normally happens mid-cycle, but since menstrual cycles can vary tremendously from person to person, it pays to keep track of yours for several months–noting when you start your period, how long it lasts and when you are ovulating (you should notice an increase in cervical mucus around ovulation). “Your most fertile days include the two or three before and after actual ovulation,” says Donovan, so plan to have intercourse several times during that time window.

Stop Smoking

You shouldn’t smoke once you’re pregnant (it can have serious negative consequences for the fetus), so it pays to quit now. As a bonus, ditching the cigarettes may actually help you get pregnant. “There is a direct connection between smoking and reduced fertility,” says Donovan. Cigarette smoke can damage the eggs and contribute to premature aging of your ovaries, and since DNA abnormalities are a leading cause of miscarriage, smoking can affect both your ability to get and to stay pregnant.

Watch Your Weight

Being either overweight or underweight can affect your hormones, throwing off your menstrual cycle and your fertility. “Polycystic ovarian syndrome (PCOS) is a metabolic condition linked to being overweight, and women who suffer from PCOS may stop ovulating,” says Donovan. Likewise, women who are underweight may lose their menstrual cycles altogether or may have irregular ovulation, making it more difficult to know when they are most fertile.

Reduce Stress

Sometimes the stress of trying to have a baby can be part of what makes it difficult to conceive. Stress causes the release of the hormone cortisol, which affects many of the body’s systems and can interfere with the normal balance of other hormones. “It can be especially hard for high-achieving women who are used to having control over when things happen,” says Donovan. “Having trouble with fertility and not having control over when you get pregnant is quite a jolt.” But being told to “just relax” can add to your stress levels. Don’t make “relaxing” just another entry on your to-do list, but try to take positive steps toward reducing the amount of stress in your daily life. Getting enough sleep, eating well, and exercising regularly can help–as can more traditional stress reduction techniques like meditation, deep breathing, yoga, massage, or acupuncture. “The key is to bring balance and peace to your life,” says Donovan. “You want your body to be a nice, peaceful environment in order to encourage pregnancy.”

Don’t Delay

Even though many women are having babies in their late 30s and early 40s, fertility clearly declines with age. In this respect, biology has not evolved as quickly as modern-day society; cultural norms may be shifting pregnancy ages later, but a woman’s quantity and quality of eggs declines significantly in her 30s.

Last modified on Thursday, 25 February 2016 06:36
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    Scientist Dr. Randal Voss gets the occasional reminder that he’s working with a kind of superstar. When he does outreach events with his laboratory, he encounters people who are keen to meet his research subjects: aquatic salamanders called axolotls.

    The amphibians’ fans tell Voss that they know the animals from the internet, or from caricatures or stuffed animals, exclaiming, “‘They’re so adorable, we love them,’” said Voss, a professor of neuroscience at the University of Kentucky College of Medicine. “People are drawn to them.”
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    Take one look at an axolotl, and it’s easy to see why it’s so popular. With their wide eyes, upturned mouths and pastel pink coloring, axolotls look cheerful and vaguely Muppet-like.

    They’ve skyrocketed in pop culture fame, in part thanks to the addition of axolotls to the video game Minecraft in 2021. These unusual salamanders are now found everywhere from Girl Scout patches to hot water bottles. But there’s more to axolotls than meets the eye: Their story is one of scientific discovery, exploitation of the natural world, and the work to rebuild humans’ connection with nature.

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    Axolotl is a word from Nahuatl, the Indigenous Mexican language spoken by the Aztecs and an estimated 1.5 million people today. The animals are named for the Aztec god Xolotl, who was said to transform into a salamander. The original Nahuatl pronunciation is “AH-show-LOAT”; in English, “ACK-suh-LAHT-uhl” is commonly used.
    Axolotls are members of a class of animals called amphibians, which also includes frogs. Amphibians lay their jelly-like eggs in water, and the eggs hatch into water-dwelling larval states. (In frogs, these larvae are called tadpoles.)

    Most amphibians, once they reach adulthood, are able to move to land. Since they breathe, in part, by absorbing oxygen through their moist skin, they tend to stay near water.

    Axolotls, however, never complete the metamorphosis to a land-dwelling adult form and spend their whole lives in the water.

    “They maintain their juvenile look throughout the course of their life,” Voss said. “They’re teenagers, at least in appearance, until they die.”

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    Axolotl problems
    As Mexico City grew and became more industrialized, the need for water brought pumps and pipes to the lake, and eventually, “it was like a bad, smelly pond with rotten water,” Zambrano said. “All of our aquatic animals suffer with bad water quality, but amphibians suffer more because they have to breathe with the skin.”
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    To add to the axolotls’ problems, invasive fish species such as carp and tilapia were introduced to the lake, where they feed on axolotl eggs. And a 1985 earthquake in Mexico City displaced thousands of people, who found new homes in the area around the lake, further contributing to the destruction of the axolotls’ habitat.

    These combined threats have devastated axolotl populations. According to the International Union for Conservation of Nature, there are fewer than 100 adult axolotls left in the wild. The species is considered critically endangered.
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    While the wild axolotls of Lake Xochimilco have dwindled to near-extinction, countless axolotls have been bred for scientific laboratories and the pet trade. “The axolotl essentially helped establish the field of experimental zoology,” Voss said.

    In 1864, a French army officer brought live axolotls back to Europe, where scientists were surprised to learn that the seemingly juvenile aquatic salamanders were capable of reproduction. Since then, scientists around the world have studied axolotls and their DNA to learn about the salamanders’ unusual metamorphosis (or lack thereof) as well as their ability to regrow injured body parts.
    In addition to their role in labs, axolotls have become popular in the exotic pet trade (though they are illegal to own in California, Maine, New Jersey and Washington, DC). However, the axolotls you might find at a pet shop are different from their wild relatives in Lake Xochimilco. Most wild axolotls are a dark grayish brown. The famous pink axolotls, as well as other color variants such as white, blue, yellow and black, are genetic anomalies that are rare in the wild but selectively bred for in the pet trade.

    What’s more, “most of the animals in the pet trade have a very small genetic variance,” Zambrano said. Pet axolotls tend to be inbred and lack the wide flow of different genes that makes up a healthy population in the wild. That means that the axolotl extinction crisis can’t simply be solved by dumping pet axolotls into Lake Xochimilco. (Plus, the pet axolotls likely wouldn’t fare well with the poor habitat conditions in the lake.)

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    Why axolotls seem to be everywhere — except in the one lake they call home
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    Scientist Dr. Randal Voss gets the occasional reminder that he’s working with a kind of superstar. When he does outreach events with his laboratory, he encounters people who are keen to meet his research subjects: aquatic salamanders called axolotls.

    The amphibians’ fans tell Voss that they know the animals from the internet, or from caricatures or stuffed animals, exclaiming, “‘They’re so adorable, we love them,’” said Voss, a professor of neuroscience at the University of Kentucky College of Medicine. “People are drawn to them.”
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    Take one look at an axolotl, and it’s easy to see why it’s so popular. With their wide eyes, upturned mouths and pastel pink coloring, axolotls look cheerful and vaguely Muppet-like.

    They’ve skyrocketed in pop culture fame, in part thanks to the addition of axolotls to the video game Minecraft in 2021. These unusual salamanders are now found everywhere from Girl Scout patches to hot water bottles. But there’s more to axolotls than meets the eye: Their story is one of scientific discovery, exploitation of the natural world, and the work to rebuild humans’ connection with nature.

    A scientific mystery
    Axolotl is a word from Nahuatl, the Indigenous Mexican language spoken by the Aztecs and an estimated 1.5 million people today. The animals are named for the Aztec god Xolotl, who was said to transform into a salamander. The original Nahuatl pronunciation is “AH-show-LOAT”; in English, “ACK-suh-LAHT-uhl” is commonly used.
    Axolotls are members of a class of animals called amphibians, which also includes frogs. Amphibians lay their jelly-like eggs in water, and the eggs hatch into water-dwelling larval states. (In frogs, these larvae are called tadpoles.)

    Most amphibians, once they reach adulthood, are able to move to land. Since they breathe, in part, by absorbing oxygen through their moist skin, they tend to stay near water.

    Axolotls, however, never complete the metamorphosis to a land-dwelling adult form and spend their whole lives in the water.

    “They maintain their juvenile look throughout the course of their life,” Voss said. “They’re teenagers, at least in appearance, until they die.”

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